antimicrobiano

Uso de antimicrobianos em pacientes oncológicos em cuidados paliativos

  • Autores:
  • Claudinei Alves Santana
  • Mirian de Freitas Dal Ben Corradi
  • Silvia de Lima Vieira
  • Wanessa Cassemiro Fernandes
  • Palavras-chave:
  • antibiótico
  • antimicrobiano
  • câncer
  • cuidado paliativo
  • infecção
  • reação adversa
Resumo: Introduction: Cancer is characterized by disorderly cell proliferation of genetic origin and has been a challenge for medicine for many centuries. Therapeutic approaches depending on the physiological reserves and the type of cancer that affects the patient can compromise important organic systems, and some patients do not respond adequately to the treatment, initiating palliative care. The use of antimicrobials at this stage is questionable due to the real benefits to patients when considering only increased survival. However, the evidence points to the use of antimicrobials in order to improve the quality of life of patients, with symptom control and the promotion of comfort. Objective of this work was to carry out a systematic review of the literature on the use of antimicrobials in cancer patients in palliative care and its adverse reactions and benefits for comfort and treatment of symptoms. Review and discussion: International literature review study in international databases (PubMed and ScienceDirect) by 2 independent researchers with the proposal to approach the theme in depth and respond to the proposed objective. From the adopted methodology, 23 articles were selected for the preparation of the review article and adverse reactions are reported in studies related to the use of antimicrobials in cancer patients, however, they were not described as the main objective of the studies and from the point of view of promoting comfort and symptom control the use of antimicrobials in the studies showed favorable results, however, with subjective responses that demonstrate the need for protocols and evaluation scores. Final considerations: Patients in palliative care and use of antimicrobials have important dilemmas in the management of end-of-life care that need to be thoroughly evaluated in relation to the benefits of the use and the presence of adverse reactions that can cause losses at this critical moment. Keywords: antibiotic, antimicrobial, cancer, infection, palliative care, adverse reaction. Expandir Resumo Acessar Texto Completo