Resumo: Introduction: Pharmaceutical Care proposes that the pharmaceutical professional acts by identifying, intervening and preventing the Problems Related to Medicines (PRM), through actions that promote rational use. Review: Systematic literature of the integrative type of relevant evidence-based studies, which were published between the years 2007 and 2020 in the Google Scholar, Lilacs, PubMed and SciElo databases, in English, Spanish and Portuguese. Discussion: The literature review allows addressing the main barriers of Pharmaceutical Care in UBS, evaluating the participation of the pharmacist and highlighting its importance in promoting access and rational use of medicines, with approaches that highlight the difficulties of insertion. Final considerations: Despite the barriers faced by the pharmaceutical professional, it is extremely important to act in front of the health team, since the pharmacist has scientific technical knowledge with regard to Pharmaceutical Care, thus promoting effective and quality care. However, it is important that the professional is inserted to carry out the actions inherent to their training, aiming at success in the users' pharmacotherapy. Keywords: pharmaceutical care, pharmacotherapeutics, PRM, rational use of medicines. Expandir Resumo Acessar Texto Completo

Resumo: Introduction: Medicines are among the main causes of intoxication identified by the Toxicological Information and Assistance Centers, occupying the first position among the agents that cause intoxication in Brazil since 1994. The pharmacist must focus on prevention, and its function is to identify and solve problems related to medications, guiding the patient on drug interactions and also on toxicity. Thus, this research aims to raise publications that show the importance of the pharmacist in the prevention of drug intoxications. Review: This is an exploratory bibliographic review, organized in an integrative literature review. The data survey comes from scientific productions published from 2018 to 2021, in Portuguese, indexed in the databases of MEDLINE-PUBMED, LILACS, SCIELO and the Ministry of Health's electronic address. Discussion: Suicide attempt prevails as the main cause of drug poisoning in the country. The fragile regulation of advertising about medicines and the ease in acquiring drugs without a medical or pharmaceutical prescription are among the causes that contribute to intoxications. The northern region has the lowest number of drug poisoning notifications in Brazil, and Tocantins is the state with the highest amount of drug poisoning in the northern region. From 2016 to 2020, 714 intoxications by toxic agents were registered, of these, about 44% of the grand total, were caused by drugs in Tocantins. Final considerations: The findings of this research proved the importance of the pharmacist in dispensing medications and in pharmacotherapeutic follow-up, as this professional can guarantee the quality and effectiveness of medications in the treatment, thus avoiding side effects, drug interactions and even toxic syndromes. Keywords: pharmaceutical attention, drug intoxication, exogenous intoxication. Expandir Resumo Acessar Texto Completo