Resumo: Introduction: The ability of bacterial resistance to antibiotics is characterized as the possibility of a bacterium to survive in concentrations of antibiotics that inhibit others of the same species. Review: This study is a literature review based on the synthesis of the main studies published in LILACS and MEDLINE that are part of the Virtual Health Library – VHL collection database. The increase in pathogenic microorganisms that resist antimicrobials due to their infectious potential is increasingly progressive. Once the antimicrobial is prescribed by the responsible physician, the pharmacist is responsible for instructing the administration of the same, which will provide greater safety and efficiency during the patient's treatment. Discussion: To reduce the incidence of antibiotic resistance due to inappropriate use, it is important that the patient has adequate information, especially with regard to not using self-medication. Final considerations: The pharmaceutical action is important in the correct orientation of antimicrobials, being a great challenge. It is essential that you actively participate in the use of medications and provide the patient with the necessary information about antibiotic therapy. Keywords: antimicrobials, resistance, pharmaceutical. Expandir Resumo Acessar Texto Completo

Resumo: The presence of antibiotic residues in milk may occur due to their deliberate addition to the animal's feed and the final product or, due to non-compliance with the latency period after administration of these drugs in dairy animals, thus leading to undesirable reactions to humans, such as hypersensitivity, bacterial resistance and imbalance of the intestinal microbiota. Thus, the objective of the research was to investigate the presence of antibiotic residues in fresh, pasteurized and UHT milk samples marketed in the cities of Bela Cruz and Sobral, located in Ceará. Ninety milk samples were analyzed, of which 30 were fresh milk, 30 pasteurized milk and 30 UHT milk. Qualitative analyzes of antibiotic residue detection in milk were performed following the instructions in the Cow Side II Test kit. Of the 90 samples studied, 63.33% were positive for the presence of antibiotics, where 70% of the fresh milk samples, 73.33% of the pasteurized and 46.67% of the UHT milk samples showed positive reaction to the presence of antibiotics. antibiotics. It was concluded that in the majority of the samples studied there was the presence of antibiotic residues and the present residues were not quantified to compare with the acceptable limit due to the qualitative kit used for the tests. It should also be noted that despite the non-quantification, the presence of these residues should still be considered a concern for consumers, as it is known that they can cause allergic reactions in individuals with hypersensitivity, as well as exposing consumers to other serious risks. Keywords: antibiotics, milk, resistance. Expandir Resumo Acessar Texto Completo