Início Aplicação de toxina botulínica no tratamento da sialorreia crônica em pacientes com...
Toxina Botulinica tipo A
Aplicação de toxina botulínica no tratamento da sialorreia crônica em pacientes com doenças neurológicas
Resumo:
Introduction: Sialorrhea is defined as the extraoral escape of saliva. It is an embarrassing condition for the affected, causing psychological damage and affecting their sociability, being also uncomfortable for their caregivers. Review: This study carried out a review of national and international scientific literature, consulted in the Scielo, PubMed and Google Scholar databases. This literature review aims to evaluate and describe the therapeutic use of botulinum toxin for the treatment of sialorrhea. Discussion: In the treatment of sialorrhea, botulinum toxin type A (TBA), produced by the bacterium Clostridium botulinum, acts by blocking the release of acetylcholine in the nerve fibers, preventing the production of saliva by the salivary glands, and, without adverse effects, in counterproposal, the other treatments presented have several side effects. Final considerations: The administration of botulinum toxin presents itself as the best alternative in relation to more invasive procedures and the use of anticholinergic drugs that can bring different types of adverse effects.
Keywords: Botulinum Toxins Type A, Salivary glands, Sialorrhea.
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