Início Farmacoterapia da trombose arterial
warfarina
Farmacoterapia da trombose arterial
Resumo:
Introduction: To present the therapeutic effects of warfarin in the treatment of arterial thrombosis and its medicinal and dietary changes. Review: This is a descriptive study, systematic literature review, through the search of electronic databases such as PubMed, Google Scholar, SciELO. The search was guided by indexing descriptors such as pharmacotherapy, arterial thrombosis, warfarin, thrombotic events, using databases from the Virtual Health Library. Discussion: The present study was carried out through a literature review to demonstrate the effect of warfarin in the treatment of arterial thrombosis, as a possible alternative anticoagulant therapy in comparison to the new oral anticoagulant drugs. Discussion: More than 200 drug and food interactions have been identified with the use of warfarin, which may enhance or decrease its effect. Thus, warfarin proved to be effective, with the advantages of being a drug that is easy to administer, low cost, besides allowing the control and monitoring of dosage according to the needs of each patient, however, the disadvantages of using warfarin about the new anticoagulants they are: Unpredictable and individual pharmacokinetics, dietary restrictions, need for frequent monitoring of INR, slow onset and compensation, long half-life. Final Considerations: As shown in this study, warfarin is an effective anticoagulant drug and more prescribed in clinical practice. arterial thrombosis pharmacotherapy
Keywords: bioavailability, bioequivalence, generic drugs.
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