Início Efeitos adversos decorrentes da terapia prolongada com corticosteroides
efeitos adversos
Efeitos adversos decorrentes da terapia prolongada com corticosteroides
Resumo:
INTRODUCTION: Corticosteroids, cortisol derivative drugs, are commonly used to treat inflamatory, alergic, immunologic and oncologic diseases. Besides their benefits, they have to be carefully used because these medicine appears associated with umpteen side effects – some of then are severe and another ones are aesthetically undesirable. REVIEW: This bibliographic review shows the main side effects associated whit corticosteroid therapy. DISCUSSION: Osteoporosis, hyperglycemia, dyslipidemia, infections, cardiovascular diseases, Cushing syndrome, immunosuppression and psychiatric disorders are the most severe side effects related with systemic, prolonged or high dosage corticosteroid therapy. FINAL REMARKS: Corticosteroids are resorted to treat a huge number of health conditions. Thereat, it is necessary to recognize and comprehen all of their side effects so they can be wariness and properly prescribed.
Keywords: Side effects, Corticosteoids, Corticosteroid therapy, Adrenal supression, Cushing syndrome, hyperglycemia, osteoporosis.
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Benefícios do uso de melatonina no tratamento de pessoas com distúrbios do sono
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Introduction: It is known that the quality of sleep significantly interferes in people's physical, mental and social health. However, during the day-to-day hustle and bust, with increasing commitments, jobs and tasks, in addition to genetic predisposition and other factors, sleep has been increasingly compromised. In an attempt to meet this need, many people have resorted to the use of anxiolytic drugs to help sleep, without considering the risks and their side effects. Review: This work was carried out through a literature review with the objective of evaluating the effects of melatonin in the treatment against insomnia, as an alternative treatment with less adverse effects compared to the commonly used benzodiazepines, especially Clonazepam. Discussion: Melatonin is a hormone produced mainly at night by the pineal gland and its main function is to induce sleep. Some factors can decrease its production, compromising the quality of sleep. Several studies have shown that the use of exogenous melatonin contributes significantly to the adjustment of the circadian cycle, improving the quality of sleep. Final remarks: Therefore, it is of utmost importance that there is a more careful look at the treatment of insomnia with less damage to health, through effective alternatives and with minimal adverse effects, in order to contribute to the quality of life of people. Melatonin proves to be a good option for this purpose. However, there is a need to improve its accessibility, allowing the expansion of its use, however, under guidelines of rational use.
Keywords: adverse effects, clonazepam, melatonin, insomnia, sleep disorders.
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Protocolos dietéticos midiáticos: características, aplicabilidade clínica e os possíveis mecanismos regulatórios
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Introduction: The practice of healthy eating is an essential method for the prevention, treatment and restoration of various diseases, therefore, the nutritional conduct must be based on scientific data on applicability, flexibility and acceptability. The objective of this work is to demonstrate, through scientific evidence, the characteristics and clinical applicability of some dietary protocols, which are in evidence in the media. A bibliographic review was carried out to address the thematic dietary media protocols: characteristics, clinical applicability, and possible regulatory mechanisms, in Portuguese, English and Spanish. The diets addressed were ketogenic, DASH (Dietary Approaches to Stop Hypertension), low FODMAP, gluten-free and paleolithic. Final considerations: The practice of a healthy lifestyle can generate countless benefits, such as prevention, cure and staging of several diseases, by doing a thorough analysis of the mechanisms and characteristics of some dietary protocols, you will find a certain degree of similarity: food balanced, diversified, individualized, indicated and accompanied by professionals in the field. Finally, it is concluded that to obtain plausible results, about the field of diets, it is essential to consider other aspects dissimilar to mass adhesion.
Keywords: dietary protocols, indications, contraindications, benefits, adverse effects.
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