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Processos fermentativos direcionados a produção de antibióticos: uma alternativa a resistência de bactérias

Resumo: Introduction: Antibiotics are drugs of great efficiency in combating bacteria and formerly one of the fermentative treatment options, being used on a large scale, mainly monensin-based compounds, which act efficiently against gram-positive bacteria, predominant contaminants in the ethanolic fermentation. This research contemplates the fermentation processes aimed at the production of antibiotics, using the Scielo, Science and Lilacs database, thus providing an alternative for the resistance of bacteria, making an approach related to the use of a fermentation process for a collection of antibiotics. Review: Antibiotics are substances produced by microorganisms that inhibit the growth of bacteria, causing their destruction. From the studies related to the development of efficient drugs to combat bacterial infections, a favorable revolution to drug treatment is obtained, reducing the drastic cause caused by microbial diseases. The production of antibiotics using aerobic fermentation processes has aroused great interest from industrialists, this statement is highlighted because the procedure for obtaining them is simple, since antibiotics can be complex molecules. Discussion: From the advances in biotechnology, there has been a great expansion of new antibiotics and drugs with high efficiency in combating microorganisms, which are increasingly resistant due to natural genetic modifications. This, in turn, may be related to the routes of synthesis and biosynthesis of antibiotics, which cannot be quite diverse. Final considerations: Through this research it was possible to obtain satisfactory results, which did not qualify that fermentation processes can be the pillar of success of biotechnology, being directed as an alternative for the resistance of bacteria to antibiotics. Keywords: antibiotics, fermentation processes, innovation. Expandir Resumo Acessar Texto Completo