Início Propriedades medicinais da Mauritia flexuosa
Artigo de Revisão
Propriedades medicinais da Mauritia flexuosa
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Introduction: The present work is about deepening the knowledge about the medicinal properties of Mauritia Flexuosa, spreading the benefits of extracting the buriti pulp regarding the healing process, inhibiting antibacterial activities, photoprotective to UV radiation and being a supplement rich for supplementation in people with Diabetes mellitus. For the construction of this work, a bibliographic survey of an exploratory nature was used, which is based on the survey of secondary scientific data and the systematization of information, and inserted in the Scielo, Pubmed and Google Scholar databases. Review: the oil obtained from the extraction of the buriti pulp when used alone does not have antibacterial activity against multidrug-resistant strains, but associated with the use of drugs with antibiotic properties potentiates the inhibitory action. Acting as a vehicle for enhancing and transporting antioxidants to prevent damage caused by UV radiation, it is a natural antioxidant capable of slowing the oxidation processes of normal physiological functions, reducing the risk of various diseases, such as DM. There is a need for incentives and the intensification of clinical studies focused on research to improve Buriti's health benefits. Discussion: Mauritia flexuosa L. f. it is part of the Arecaceae family, one of the palm trees with a large distribution index in the national territory, it is considered the symbol palm of the cerrado. One of the main chemical constituents are natural antioxidants that form vitamin E, tocopherols. It can be said that in the oil obtained from the pulp of the fruits of the genus Mauritia flexuosa there are substances that promote benefits in the healing process, Mauritia flexuosa does not show antibacterial activity against very resistant strains when used alone, but when associated with antibiotics, there was potentiation of the action of some drugs, considered as a potentiating vehicle and carrier of antioxidants to prevent damage caused by UV radiation, precisely because it has photo protective properties, which helps in the recovery of the epidermis after sun exposure, that nutrition with buriti flour promoted a reduction of oxidative damage to biomolecules. Final considerations: Through this research it was possible to elucidate that Mauritia Flexuosa has a curative capacity when used in conjunction with specific drugs, thus having a great potential benefit when used correctly.
Keywords: Buriti, Mauritia flexuosa, medicinal plants, Cerrado, pharmacology.
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A importância do farmacêutico na prevenção de intoxicações medicamentosas – uma revisão integrativa
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Introduction: Medicines are among the main causes of intoxication identified by the Toxicological Information and Assistance Centers, occupying the first position among the agents that cause intoxication in Brazil since 1994. The pharmacist must focus on prevention, and its function is to identify and solve problems related to medications, guiding the patient on drug interactions and also on toxicity. Thus, this research aims to raise publications that show the importance of the pharmacist in the prevention of drug intoxications. Review: This is an exploratory bibliographic review, organized in an integrative literature review. The data survey comes from scientific productions published from 2018 to 2021, in Portuguese, indexed in the databases of MEDLINE-PUBMED, LILACS, SCIELO and the Ministry of Health's electronic address. Discussion: Suicide attempt prevails as the main cause of drug poisoning in the country. The fragile regulation of advertising about medicines and the ease in acquiring drugs without a medical or pharmaceutical prescription are among the causes that contribute to intoxications. The northern region has the lowest number of drug poisoning notifications in Brazil, and Tocantins is the state with the highest amount of drug poisoning in the northern region. From 2016 to 2020, 714 intoxications by toxic agents were registered, of these, about 44% of the grand total, were caused by drugs in Tocantins. Final considerations: The findings of this research proved the importance of the pharmacist in dispensing medications and in pharmacotherapeutic follow-up, as this professional can guarantee the quality and effectiveness of medications in the treatment, thus avoiding side effects, drug interactions and even toxic syndromes.
Keywords: pharmaceutical attention, drug intoxication, exogenous intoxication.
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Assistência farmacêutica em unidades hospitalares em tempos de pandemia – uma revisão integrativa
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Introduction: The COVID-19 pandemic imposed on hospital pharmacists the need to plan and organize a response to the challenges brought about by the disease. Pharmacists exercise fundamental activities in the context of the pandemic, either through the supply of medicines or the provision of pharmaceutical services. Managing pharmacies, hospitals or community, in times of SARS-CoV-2 is a new challenge. The hospital pharmacy has been facing several challenges in the face of the pandemic scenario and, in order to continue offering a quality service to the population, it was necessary to adopt coping strategies and adapt their activities. Thus, this research aims to highlight the importance of pharmacists and pharmacies within hospital units, considering the specificities of the pandemic of COVID-19. Review: This is an exploratory bibliographic review, through an integrative review. The collection of scientific data and the systematization of information come from scientific productions published from 2018 to 2021, in Portuguese, indexed in the database of the BVS, LILACS and SCIELO. Discussion: Hospital pharmacists had to restructure the service in response to COVID-19, considering the need to protect the teams, so that there is no compromise in the care activity and support for medical action and, simultaneously, provide an effective response to the new reality, not neglecting the component of reviewing and monitoring the use of health technologies and active pharmacovigilance of drugs used in the treatment of COVID-19. Final Remarks: It was found that the concept of hospital pharmacy goes beyond a sector of custody of medicines, being a department that adds value to other sectors of the hospital. Thus, the research findings allowed us to conclude that pharmacists, when working in hospital pharmacies, can collaborate with the multiprofessional health team, monitoring the use of medicines and the clinical evolution of patients, since the off-label use of medicines is a current reality that can cause serious damage to the health of individuals.
Keywords: pharmaceutical assistance, pharmacist, hospital pharmacy, pandemic.
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Farmacoterapia da trombose arterial
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Introduction: To present the therapeutic effects of warfarin in the treatment of arterial thrombosis and its medicinal and dietary changes. Review: This is a descriptive study, systematic literature review, through the search of electronic databases such as PubMed, Google Scholar, SciELO. The search was guided by indexing descriptors such as pharmacotherapy, arterial thrombosis, warfarin, thrombotic events, using databases from the Virtual Health Library. Discussion: The present study was carried out through a literature review to demonstrate the effect of warfarin in the treatment of arterial thrombosis, as a possible alternative anticoagulant therapy in comparison to the new oral anticoagulant drugs. Discussion: More than 200 drug and food interactions have been identified with the use of warfarin, which may enhance or decrease its effect. Thus, warfarin proved to be effective, with the advantages of being a drug that is easy to administer, low cost, besides allowing the control and monitoring of dosage according to the needs of each patient, however, the disadvantages of using warfarin about the new anticoagulants they are: Unpredictable and individual pharmacokinetics, dietary restrictions, need for frequent monitoring of INR, slow onset and compensation, long half-life. Final Considerations: As shown in this study, warfarin is an effective anticoagulant drug and more prescribed in clinical practice. arterial thrombosis pharmacotherapy
Keywords: bioavailability, bioequivalence, generic drugs.
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Após o fim de um relacionamento amoroso: uma revisão narrativa
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Introduction: Relationships are considered extremely important and constitute part of the formation, maturation and development process of human life. Objective: Therefore, this article aims to understand the possible impacts of ending love relationships and their emotional and behavioral implications in the subject's life. Method: To this end, a narrative literature review was carried out divided into three stages, the first: the initial search process, the second: the exclusion of articles without the eligible criteria for inclusion, and the third: full reading of the remaining articles. 32 articles were chosen for the final sample of this study. Results: In view of the evidence systematically collected, it can be seen that the changes in the post-breakup of a love relationship, at a psychological level, can be understood in two ways: positive and negative. Standing out in the first: feeling of relief, positive memories, feeling of freedom, and in the second: the prevalence of anxiety, depression, anguish, anger, sadness, grief, low self-esteem and the feeling of helplessness. Regarding behavioral changes, harassment, provocation and criminal behaviors were noticeable. Final considerations: It is concluded, therefore, that love relationships have significant implications in the life of those who pass by, especially from the point of view of negative psychological and behavioral impacts, despite considerable positive psychological effects that are subject to further investigation. In addition, by mapping the findings about the psychological and behavioral implications of the end of a love relationship, it became possible to organize in a single place the main findings that corroborate for the elucidation and expansion of the debate regarding this theme, resulting, therefore, in greater accessibility to this information, especially in the context of Brazilian literature.
Keywords: psychological distress, romantic relationship, romantic relationship breakup, psychological symptoms, behavior.
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O paciente com câncer, cognições e emoções oriundas da dor: uma revisão literária a partir de uma perspectiva psicológica
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Introduction: Oncology psychology has as its main characteristic the study of emotional actions based on oncology, aiming at providing care not only to the patient but also to their family nucleus, considering the awakening of the patient's emotions and helping this area of expertise. Review and discussion: This study corroborates the understanding of national research that address the psychological suffering of cancer as well as the emotions developed in the face of treatment, defining the characteristics of pain in this context and observing how the patient defines the stages experienced by him, understanding pain as an aspect emotional and not just physical. Final considerations: Based on these aspects, we present the incidence and prevalence of cancer, characterizing issues related to pain and its impacts in relation to neural and emotional issues, thus contributing to the development of assertive practices with regard to cancer patients, broadening the vision for the subject and its demands.
Keywords: oncology, psychology, cancer.
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Riscos do uso indiscriminado de AINES em idosos
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Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most prescribed and marketed drugs worldwide. The increase in the number of chronic diseases in the elderly is considered one of the main diseases of the aging process, and because of this the consumption of medicines has also increased in this age group. A study conducted in several Brazilian cities shows that an average of 70-90% in this age group use medications continuously, with an average of two to five medications per person. Review: The present study is a bibliographical survey of an exploratory nature, based on the survey of secondary scientific data and the systematization of information. From databases such as SCIELO, MEDLINE, PUBMED, PUBSAUDE, Manuals of the Ministry of Health, using as cut-off date the last 20 years (2000-2020). Studies published in Spanish, Portuguese and English were considered suitable. Studies not dealing with the subject, about the elderly, self-medication or anti-inflammatory drugs, studies in other languages, or studies prior to the cut-off date were excluded from the search. Discussion: NSAIDs should be prescribed with more caution and specific orientation for each individual patient, specifically the older ones. Even with all its quality and effectiveness in the treatment of pain and inflammation of chronic diseases. The sale of this class of drugs needs to be more restricted, and the easy access to this class in drugstores contributes to indiscriminate use and the worsening of the general health condition of the elderly, who already have some disease in their clinical diagnosis, contributing to possible drug interactions. Final considerations: Nonsteroidal anti-inflammatory drugs can cause several risks to the patient's health if not used correctly. It is necessary to pay special attention to the dispensation and orientation of the elderly patient on the correct use of the drug and possible interventions with other methods to treat their diseases
Keywords: anti-inflammatorium, idoses, indiscriminated use, health risks, adverse reactions.
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A importância do controle de qualidade nos laboratórios de análises clínicas – uma revisão integrativa
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Introduction: Modern clinical analysis laboratories are an important part of the health system, as laboratory results are responsible for up to 75% of the information needed to decide on drug treatment. Thus, this research, through a bibliographic review, sought to demonstrate the importance of implementing and maintaining quality control in a clinical analysis laboratory. Review: This is an integrative literature review. The collection of scientific data and the systematization of information come from scientific productions published from 2011 to 2021, in Portuguese, indexed in the database of the BVS, MEDLINE-PUBMED, LILACS and SCIELO. Discussion: The need to implement quality control and management standards in health care services has shown significant growth in recent years. The implementation of a quality control system can result in several benefits, such as reduced costs and waste, increased laboratory profits, increased laboratory competitiveness and the establishment of business confidence in the market. Final considerations: Although there is a technological transformation that has taken place in the laboratory environment, errors still happen. The main source of errors continues to come from human activities, which reinforces the need to implement quality controls in the different phases of laboratory analysis in order to reduce this interference, reducing costs arising from rework and, consequently, increasing the service credibility.
Keywords: quality control, PALC standard, laboratory quality.
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Qualidade dos medicamentos genéricos no Brasil – Revisão
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Introduction: Describe the history and quality of generic drugs, from production to dispensing generic drugs in Brazil. Revision: It was a narrative review addressing the main points such as the creation, effectiveness, bioavailability and equivalence of the generic drug. Discussion: The implementation of Law 9,787 of 1999, which authorizes the sale of generic drugs by any laboratory and standardized packaging whose patents have expired. Generic drugs entered the market with more affordable prices for the population, thus having the possibility to choose the reference drugs. Through this law, new drugs and guidelines were produced following the standards, quality control, bioavailability, bioequivalence, among others, with the purpose of proving the efficacy of the generic drug with that of the reference. Final considerations: Thus, it is possible to conclude that generic drugs since their inclusion in the market have become a great advance for Brazilian society in industries, pharmacies, having the same therapeutic profile and with cost benefit and viable access for all.
Keywords: bioavailability, bioequivalence, generic drugs.
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O uso da própolis como agente cicatrizante e hepatoprotetor
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Introduction: Propolis has been used since its discovery as an anti-inflammatory agent, among other purposes, in view of its beneficial effects, it emerged with the evolution of the need to initiate new studies, researchers discovered, more than 300 compounds, which in its most are in forms of polyphenols, antioxidants that fight disease and damage to the body. Propolis is derived from different parts of the plant, such as buds, flower buds and resinous exudates. This work aims to understand the main benefits of using propolis as a healing and hepatoprotective agent. For the development of this, the articles were selected from a previous reading of the abstracts in order to compare the respective points proposed, used and discussed by the author. Review: According to the literature, the application of propolis increases the rate of wound healing and re-epithelialization of diabetic wounds in rodents. Research has shown that, with a single topical propolis, there is increased wound healing in a diabetic rodent model of full-thickness skin healing. Regarding the use of propolis as a hepatoprotector, they state that, as the liver is the main organ for the metabolism of compounds, many liver diseases appear due to its exposure to toxic substances, and the oxidative stress promoted by these substances is very important in the pathophysiological mechanisms of these diseases. Discussion: Propolis has positive results as a healing agent by reducing the inflammatory response, however, its hepatoprotective power is low, due to its oral administration. Final Considerations: You can say that propolis has good results for tests as healing and hepatoprotective, but new tests must be developed to evaluate its effects, as well as pharmaceutical forms and administration routes for a better pharmacological result.
Keywords: propolis, healing, hepatoprotective, extract, pollen.
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Uso indiscriminado dos opioides e suas consequências
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Introduction: Opioids belong to a class of drugs used as analgesics for acute and chronic pain, are classified as natural, semi-synthetic and synthetic. They are prescribed in the treatment of postoperative pain and chronic when there is no response of common or weaker analgesics being effective in painful managements, however the use indiscriminately rings several health risks both physical and psychological. Review: From the methodology, 34 articles were selected because they were in accordance with the theme. This is a systematic literature review the search was done through the Google Academic and Scientific Electronic Library Online databases. Discussion: They are drugs widely administered for their powerful and rapid action, however, the adverse effects of opioids are also common, among them: respiratory depression, constipation, itching, drowsiness and nausea/vomiting. Prescribing opioids consciously and rationally is still a challenge for trained health professionals. Final considerations: Pharmacists may contribute to adequate prescriptions of opioids also understanding the needs of access to opioids so more research on pain and the disorder of the abuse of these drugs is essential, constant reinforcement in the education of prescribers and guarantee access to effective treatments of these medicines.
Keywords: toxicological effects, opioids, indiscriminate use.
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Eficiência de braquetes convencionais e autoligados considerando seu atrito e expressão de torque durante o tratamento
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Introduction: Conventional and self-ligating brackets are commonly evaluated in relation to their efficiency differential in orthodontics, leading to the understanding that self-ligating brackets have less friction, due to their absence of elastic bandages, allowing for better sliding, while conventional brackets with elastic bandages provide greater friction. The efficiency levels are compared between the models of brackets on the market, evaluating in addition to friction, their torque expression during treatment. Review and discussion: The consequent study proposed to implement a literature review on the subject, analyzing the efficiency differential between the models of conventional and self-ligating brackets. Final considerations: In conclusion, through the referenced scientific articles, there is insufficient evidence of the superior efficiency of self-ligating brackets in relation to conventional brackets, but rather, differentials during treatment.
Keywords: friction, orthodontic brackets, efficiency, torque.
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Toxicidade do Tabaco: uma revisão integrativa sobre a periculosidade advinda de um mal lícito que assola o mundo
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Introduction: 9.8% of the Brazilian population has a smoking habit. A WHO study found that smoking is responsible for the deaths of more than 8 million people each year. In Brazil, tobacco dependence causes approximately 157 thousand deaths per year, which generates an annual cost to society of approximately R $ 57 billion. Smoking is the leading cause of preventable death in the world. It is an epidemic health condition that causes physical, psychological and behavioral dependence. Smoking is estimated to be related to about 50 diseases. Thus, this research aimed to raise publications that show the danger that the use of tobacco can cause human health. Review: It is an integrative literature review. The collection of scientific data and the systematization of information come from scientific productions published since 2015, in Portuguese and English, indexed in the database of MEDLINE-PUBMED, LILACS and SCIELO. Nicotine affects the respiratory system and causes several damages to the smoker's health, such as chronic obstructive pulmonary disease, interstitial diseases, asthma exacerbations, among others. Coronavirus can pose an additional threat to smokers, with smoking being seen as a risk factor for admission to the ICU and mortality in inpatients treated for COVID-19. Discussion: Although tobacco production moves the economy, on the other hand, there is a much higher percentage of spending on health treatments. Tobacco use in youth has been spreading and making young people more prone to addiction, affecting their health. Final remarks: Tobacco consumption is extremely harmful to health. Considering the high cost that this habit causes, massive campaigns supported by the public power, should be stimuli aiming at guiding, regarding the risks of the use of this harmful and avoidable habit.
Keywords: cigarette, licit drugs, nicotine, tobacco.
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O uso de fitoterápicos no tratamento de doenças reumáticas e diabetes
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The research carried out in search of herbal ingredints has revealed the medicinal property of a vast species of plants, contributing whith a more concretebibliographic and scientific base, in the prescription of such herbs for known pathologies such a rheumatinsm an diabetes. Througth these searches, the studies have brought considerable results,whitch makes it possible to use them in the tratament of various pathologies, including rheumatic diseases, and insulin disorders. Therefore, extracts from natural sources such as medicinal plants often have excellent pharmacological action and no or negligible adverse effects. The present research aims to address the use of herbal medicines in the treatment of rheumatic diseases and diabetes, having as main objectives the use of these as alternatives in the treatment of these respective diseases, as well as the role of the pharmaceutical professional in the face of these pathologies. Finally, this article demonstrates both the acceptance of herbal medicines by the general population, as well as their low investment and high effectiveness of the medication.
Keywords: insulin, medicinal plants, rheumatism.
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Pandemia do SARS-COV-2: uma revisão integrativa sobre os principais medicamentos, aprovados ou em fase de estudos, que podem ser utilizados no tratamento da COVID-19
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Introduction: SARS-CoV-2 infection is the largest public health emergency of international importance ever declared. The large number of loss of life is added to the difficulties related to the management of the disease, even with no effective treatment available. Remdesivir, Azithromycin, Dexamethasone, Ibuprofen and Chloroquine are some of the drugs under testing for possible use in the treatment against Covid-19. Review: This study addresses a bibliographic review, of the integrative type. For the composition of this study, scientific publications and pronouncements of health agencies in Portuguese and English, published until April 2021 were used. Discussion: Few drugs have shown any effect in fighting the pandemic. In the absence of specific medications or vaccines in sufficient quantity, the alternative to avoid the collapse of health systems, consisted of combining a policy of social isolation with the testing of the population. Final considerations: Despite the efforts of the scientific community, there is no specific treatment to block viral replication, there are drugs that help in the treatment of the symptoms of the disease. At the moment, when there is a growth in new cases and hospitalizations, only mass vaccination will have an impact in reducing deaths and hospitalizations in a short interval.
Keywords: covid-19, coronavirus, pharmacological treatmen.
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Qualidade de vida dos profissionais de enfermagem que conciliam trabalho e estudo em um centro universitário privado na cidade de Recife/PE
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Introduction: A quality of life according to the World Health Organization (WHO) is a perception of the individual when his position of life in his life and his value system without which he is inserted, in relation to his objectives, of life and concerns. The objective was to evaluate the factors that interfere in the quality of life of nursing professionals that reconcile work and study. Centro Universitário Estácio do Recife / PE. Characterize the socioeconomic profile of these nursing students and identify the stressors that interfere in quality of life. Material and methods: A descriptive exploratory cross-sectional study with a quantitative approach was carried out at Estácio University Center in Recife-PE. The population was composed of graduate undergraduate nursing students duly enrolled in the 6th and 7th Periods of morning and night. In the period of October and November of 20017. Two questionnaires were used as instruments, one of the demographic data and the other of the QOL Assessment, WHOQOL-Bref. Results and discussion: Social characterization of an edition of the presented sample: female, age group of 32 to 37 years; singles; they had two children; they resided in the capital; studied from 03 to 04 days, with a workload of 10 to 15 hours per week; 01 work contract of 40 hours per week and 12x36 regime. Regarding the study of the WHOQUOL-Bref instrument, which provides, through the results, significant answers, such as: satisfaction with quality of life, living conditions; energy capacity and, on the other hand, worrying, such as: financial dissatisfaction, lack of medical treatment, among others. Final considerations: The results show the importance of implementing a strategy that aims to improve the quality of life of these nursing professionals in the physical, social, environmental and psychological domains.
Keywords: quality of life, measuring instruments, health promotion.
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Os principais riscos da hipovitaminose D na gestação – Revisão
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Introduction: Hypovitaminosis D is identified as a public health problem in many countries, and pregnant women are identified as a high-risk group, in which the prevalence ranges from 20% to 40%.This is an integrative literature review. The collection of scientific data and the systematization of information come from scientific productions published since 2015, indexed in the database of MEDLINE-PUBMED, LILACS and SCIELO. Review: In Brazil, pre-eclampsia and eclampsia are the main causes of death in pregnancy. Studies indicate that vitamin D supplementation is able to prevent these pathologies from manifesting during pregnancy. There is a consensus in the literature to routinely supplement this nutrient from the 12th week of gestation onwards. Hypovitaminosis D, has framed pregnant women in a high-risk group, which needs to be monitored and studied, with gestational diabetes mellitus as the main pathology identified in the bibliography as the cause. Discussion: Vitamin D plays an important role in all stages of pregnancy and maternal deficiency of this hormone negatively affects the newborn's skeletal, cardiovascular, respiratory and brain functions. Final considerations: The evidence presented in this work indicates an association between vitamin D deficiency with levels below 20 ng / mL and the increasing risk of progressing with premature birth, and it is also related to multiple adverse pregnancy complications, such as pre-eclampsia and low body weight of the baby.
Keywords: pregnancy, hypovitaminosis, vitamin D.
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Processos fermentativos direcionados a produção de antibióticos: uma alternativa a resistência de bactérias
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Introduction: Antibiotics are drugs of great efficiency in combating bacteria and formerly one of the fermentative treatment options, being used on a large scale, mainly monensin-based compounds, which act efficiently against gram-positive bacteria, predominant contaminants in the ethanolic fermentation. This research contemplates the fermentation processes aimed at the production of antibiotics, using the Scielo, Science and Lilacs database, thus providing an alternative for the resistance of bacteria, making an approach related to the use of a fermentation process for a collection of antibiotics. Review: Antibiotics are substances produced by microorganisms that inhibit the growth of bacteria, causing their destruction. From the studies related to the development of efficient drugs to combat bacterial infections, a favorable revolution to drug treatment is obtained, reducing the drastic cause caused by microbial diseases. The production of antibiotics using aerobic fermentation processes has aroused great interest from industrialists, this statement is highlighted because the procedure for obtaining them is simple, since antibiotics can be complex molecules. Discussion: From the advances in biotechnology, there has been a great expansion of new antibiotics and drugs with high efficiency in combating microorganisms, which are increasingly resistant due to natural genetic modifications. This, in turn, may be related to the routes of synthesis and biosynthesis of antibiotics, which cannot be quite diverse. Final considerations: Through this research it was possible to obtain satisfactory results, which did not qualify that fermentation processes can be the pillar of success of biotechnology, being directed as an alternative for the resistance of bacteria to antibiotics.
Keywords: antibiotics, fermentation processes, innovation.
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Benefícios do uso de melatonina no tratamento de pessoas com distúrbios do sono
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Introduction: It is known that the quality of sleep significantly interferes in people's physical, mental and social health. However, during the day-to-day hustle and bust, with increasing commitments, jobs and tasks, in addition to genetic predisposition and other factors, sleep has been increasingly compromised. In an attempt to meet this need, many people have resorted to the use of anxiolytic drugs to help sleep, without considering the risks and their side effects. Review: This work was carried out through a literature review with the objective of evaluating the effects of melatonin in the treatment against insomnia, as an alternative treatment with less adverse effects compared to the commonly used benzodiazepines, especially Clonazepam. Discussion: Melatonin is a hormone produced mainly at night by the pineal gland and its main function is to induce sleep. Some factors can decrease its production, compromising the quality of sleep. Several studies have shown that the use of exogenous melatonin contributes significantly to the adjustment of the circadian cycle, improving the quality of sleep. Final remarks: Therefore, it is of utmost importance that there is a more careful look at the treatment of insomnia with less damage to health, through effective alternatives and with minimal adverse effects, in order to contribute to the quality of life of people. Melatonin proves to be a good option for this purpose. However, there is a need to improve its accessibility, allowing the expansion of its use, however, under guidelines of rational use.
Keywords: adverse effects, clonazepam, melatonin, insomnia, sleep disorders.
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Gestão de Dados de Pesquisa: um desafio para os Programas de Pós-Graduação em Enfermagem
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Introduction: Open Science opens new horizons for the researcher and for academic and scientific activities. It has been growing in all areas of knowledge and comes in the nursing domain as a huge challenge to be faced. This article aims to show the path that the Nursing Postgraduate Programs at the Federal University of the Rio de Janeiro State are following to achieve a proper data management of their research, align to the scope of open science. Review and Discussion: For this purpose, it was necessary; contextualize the concept of open science emphasizing data management practices; presents the data life cycle, the FAIR principles and their application in the GO FAIR Brazil Health - Nursing network created with the purpose of elaborating strategies for the implementation of the FAIR principles in the nursing field, aiming the sharing and reuse of these data in new research. Final considerations: The coordination of the Graduate Nursing Programs at UNIRIO and the Alfredo Pinto Nursing School, from the GO FAIR Brazil Saúde Network - Nursing represents an example of the adoption of open science practices within graduate courses. Therefore, it is expected that through the studies and events that begin within the scope of the GO FAIR Brazil Health – Nursing Network, carried out in 2020 and scheduled for the following years, answer the question asked in the introduction of this article and contribute to the promotion and implementation of training strategies for students and health professionals, in general, on the management of research data in the field of nursing.
Keywords: nursing, open science, open data, FAIR principles, GO FAIR.
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Interação Fármaco-Nutriente: uma revisão sistemática
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Introduction: This study aims to review the published scientific articles about the drug - food interaction. Review: For the purpose of this research, articles published between 2014 and 2021 were selected, made available in databases such as PubMed, sciELO, CAPES journals and Google Scholar. For the selection of articles, presentations that demonstrated the mechanisms of drug - food interactions in a more succinct manner or that held a specific study group were used as criteria. For this purpose, 97 article abstracts were read, 55 articles were read in full and 20 of them were selected to support this review. Discussion: Thus, it is possible to extract from this review the great importance of having knowledge of these interactions, since it was ascertained in all publications read the recurrence of these interactions and how harmful they can be to the patient if the effectiveness of the treatment decreases. Final considerations: Thus, by knowing the main drug interactions, it is possible to direct the patient to an efficient therapy, without containing a harmful drug-nutrient relationship, and, consequently, increase the effectiveness of the treatment and reduce eventual collateral damage.
Keywords: drugs, pharmacological interactions, nutrient.
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Uso de fitoterápicos na atualidade: uma revisão de literatura
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Introduction: This work is a literature review on the use of herbal medicines today, with the purpose of presenting, based on scientific literature and articles, how is the use of these herbal medicines today. For the construction of this work, the criteria for descriptors were used, being phytotherapics nowadays, main pathologies, legislation of phytotherapics and process of obtaining phytotherapics, and inserted in the databases Scielo, Pubmed and Lilacs. The inclusion criteria are the use of articles with a time interval between 2010 and 2021, those with DOI, which can be in Portuguese, English and Spanish. For the exclusion criteria, articles that do not include the proposed period, those that do not have a DOI, incomplete ones and without titles will not be used. Review: Herbal medicines have been used by individuals since ancient times, whose purpose is the relief of pain and also curative. Although their use is old and we have a diversity of plants, they must be studied and tested clinically, so that they have the approval of the competent regulatory bodies. Discussion: With the strong adhesion of herbal medicines, this market is growing and with that, the industries are adapting for research and production on a large scale. Along with this expansion, there is a need for government incentives and especially the intensification of clinical studies aimed at the expansion of herbal medicines. Final considerations: Through this research it was possible to elucidate how is the current market of herbal medicines, stating that it is expanding.
Keywords: phytotherapics, current market, legislation and challenges faced.
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Enfermagem obstétrica e o parto humanizado
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Introduction: Childbirth care has undergone changes, becoming highly technological. This technocratic model is very ingrained in professional practices, valuing technology as a sign of successful delivery, leading to the indiscriminate use of unnecessary interventionist practices, in addition to inhumane care. Review: The objective of the article was to identify how nursing care can help to value humanized childbirth. The realization of this article was through a literature review, researching information on government health programs and published articles that addressed the subject. Discussion: 13 references were selected for the study, nine scientific articles (two in English and seven in Portuguese), two government programs, a book and a publication by the World Health Organization. Final remarks: It was concluded that the humanization of care it is fundamental and involves not only the interaction of the nurse with the parturient, but a whole range of interrelationships, involving government programs focused on the humanization of care, dedication to humanization by hospital managers, which reaches the health team and other employees institution, thus encompassing the entire system where the patient is inserted.
Keywords: obstetric nursing, humanized birth, obstetric violence.
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Impacto da exposição gengival na estética do sorriso
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Introduction: Currently, the search for aesthetics is growing in dental offices. The complaint of the gingival condition of the smile is a factor that causes great dissatisfaction in the aesthetics of the smile and has a negative impact on the perception of others, affecting the social, personal and professional life of the patients. For a satisfactory result in the treatment of this condition, it is necessary to outline an individualized treatment plan for each patient, making a correct diagnosis of the etiology of the gingival smile, as well as the most appropriate treatment for each case. The aim of the present study was to carry out a literature review on the aspects that influence the aesthetics of the smile, the different etiologies of the gingival smile and the treatment possibilities for each case. Review: The databases used for the bibliographic search were: PubMed, Google Scholar and Scielo with scientific publications dated between 1965 and 2020. Discussion: Studies have shown that the complaint of gingival smile is a factor that causes a great deal dissatisfaction in the aesthetic of the smile and generates a negative impact on the perception of others, affecting the social, personal and professional lives of patients. In addition, the gingival smile has a different etiology, which can be isolated or combined, so the treatment of this condition requires multidisciplinary work. Final considerations: In order to achieve a satisfactory result in the treatment of this condition, it is necessary to draw up an individualized treatment plan for each patient, making a correct diagnosis of the etiology of the gingival smile and later, choosing the most appropriate treatment for each case.
Keywords: periodontics, gingival overgrowth, smiling esthetics, dental.
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Tipos de tratamento para o câncer de mama
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Background: At the moment breast cancer is one of the most common types of cancer in women worldwide, atthe fifth position of cancer that causes the most death in the world. Objective: The respective study focused on describing the types of treatments for breast cancer, in view of the therapeutic efficacy of the main types of treatments contextualizing the importance of appropriate treatment. Methods: The methodology applied is a descriptive bibliographic review research, with the purpose of deepening the knowledge about breast cancer, and the main types of treatments used in this neoplasm. Conclusions: Early detection of the disease is essential to obtain a prognosis and a satisfactory treatment that helps in the survival of patients, aiming at the elimination of the tumor in the patient's body.
Keywords: prognosis, breast cancer, treatments, tumor.
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Medidas preventivas para diminuição no risco de pneumonia associada à ventilação mecânica
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Introduction: Invasive mechanical ventilation exposes patients to the risk of acquiring pneumonia associated with mechanical ventilation, which causes high rates of prolonged hospitalization, increased hospital costs and consequent worsening of the clinical picture, increasing the mortality of these patients. Such aspects make pneumonia associated with mechanical ventilation the second main infection related to health care in an intensive care unit. Review: Through the literature review methodology, this study aimed to identify, know and reinforce preventive measures performed by nursing care, capable of reducing the incidence of pneumonia associated with mechanical ventilation in an intensive care unit. Discussion: 22 references were selected, including 19 scientific articles, a book and two publications by health organizations, all in Portuguese. Final considerations: Based on the consulted literature, it was concluded that adherence to preventive measures is a powerful instrument to define strategies that increase the quality of health care in patients in intensive care units in invasive mechanical ventilation. It is suggested that educational measures aimed at the implementation of bundles for the prevention of pneumonia associated with mechanical ventilation be developed for the entire health team that works in an intensive care unit, especially for the nursing team, whose professionals are the ones who most are related to this type of care.
Keywords: Pneumonia associated with mechanical ventilation, artificial respiration, nursing care.
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